Tautomeric equilibrium of cyclic β-ketoester enamines

Iridium-catalyzed asymmetric hydrogenation of cyclic enamines.

The first highly enantioselective iridium-catalyzed hydrogenation of cyclic enamines has been developed. This new reaction provided an efficient method for the synthesis of optically active cyclic tertiary amines including natural product crispine A.

Acetylation of Some Cyclic Enamines With Substituted Acetyl Chlorides

Acylation reaction of a variety of cyclic ketones via acylation of the corresponding enamines is welldefined in the literature. Enamine acylation of carbonyl compounds is a significant synthetic method because of its mildness and the ease of preparing various β-diketones [1-4]. Acylation reactions are performed by means of converting enamines to the enaminoketones and subsequent hydrolysis of t...

Preparation of Cyclic N-tert-Butylsulfonyl Enamines by Rh(II)-Mediated Ring Expansion of a-Diazoesters Cyclic N-tert-Butylsulfonyl Enamines

Asymmetric aldol reactions of α,β-unsaturated ketoester substrates catalyzed by chiral diamines.

Highly efficient asymmetric aldol reactions between α,β-unsaturated keto esters and acyclic ketones catalyzed by chiral diamines are reported. The corresponding products were obtained in excellent yields with excellent enantioselectivities. The absolute configuration for the product was determined by X-ray analysis. A variety of substrates were tolerable in the present catalytic system.

Stereoselective intermolecular formal [3+3] cycloaddition reaction of cyclic enamines and enones.